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[DOI] [PMC free article] [PubMed] [Google Scholar] 37.Tangney C.C., Tang Y., Evans D.A., Morris M.C

Total (56% versus 50% of body weight) and extracellular body water (20% versus 15% of body weight), as well as exchangeable sodium, were shown to be increased in acromegalic patients compared to healthy subjects, whereas no differences were noted in intracellular water content [56, 101]

The microneedling overcomes the topical delivery challenge that the review identifies getting GHK-Cu to the dermal papilla cells identified by the gene data as key targets